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Dickey’s lab commenced researching mucin secretion two decades in the past and Beforehand discovered The real key genes and proteins involved, displaying how synaptotagmin and also a SNARE elaborate, just like that located in neurons, contribute to The important thing process of Ca2+-activated membrane fusion.
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“Mucus is a substantial trouble in pulmonary medicine, simply because in people with these widespread lung illnesses, thick mucus can block the airways and trigger signs and symptoms ranging from a delicate cough to pretty significant decreases in lung functionality,” reported Burton Dickey, M.
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A multicenter research staff created the 1st drug to treat the uncontrolled secretion of mucins from the airways. Experimental drug minimizes airway mucus that exacerbates typical lung health conditions.
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